Allele/Variant

Tg(RP23-326M22)760She

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

Rai1 BAC transgene
Rai1 transgene

Description

This transgene consists of the C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-326M22 (GenBank id AC096624), which contains the entire coding sequence of the retinoic acid induced 1 (Rai1) gene. The BAC also includes the sterol regulator element binding transcription factor 1 gene (Srebf1; formerly Srebp1) and the 3' end of Tom1l2. Founder line 760 has integrated ~4 copies of the transgene at a single site. Overexpression of Rai1 in the brain and liver was verified by quantitative RT-PCR and western blot analysis.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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