Allele/Variant

Fgf22tm1Dgen

Species
Mus musculus
Symbol
Fgf22tm1Dgen
Category
allele
Allele of gene
Fgf22
Transgenic Constructs
None
Synonyms
None
Description
Exon 1 and a part of exon 2 was replaced with the neomycin-resistant gene. The absence of transcript expression was confirmed by in situ hybridization.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal synaptic vesicle clustering
MGI
abnormal synaptic vesicle morphology
MGI
abnormal synaptic vesicle number
MGI
decreased miniature excitatory postsynaptic current frequency
MGI
decreased susceptibility to pharmacologically induced seizures
MGI
enhanced paired-pulse facilitation
MGI
increased synaptic depression
MGI
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Disease Associations

No data available