Allele/Variant

Adam17tm1Srj

Species
Mus musculus
Symbol
Adam17tm1Srj
Category
allele
Allele of gene
Adam17
Transgenic Constructs
None
Synonyms
  • ADAM17exneo
Description
An FRT flanked neo with a 5' loxP site was inserted upstream of exon 11. An artificial exon (11a) was created in intron 11 by inserting a cryptic splice donor site upstream of an existing cryptic acceptor site in intron 11. If spliced in, exon 11a creates a truncated CDS owing to an in-frame stop codon at the 5' end. A loxP site was inserted at the 3' end of exon 11a.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations