Allele/Variant

Serpina6tm1.1Mmp

Species
Mus musculus
Symbol
Serpina6tm1.1Mmp
Category
allele
Allele of gene
Serpina6
Transgenic Constructs
None
Synonyms
  • Cbg knockout
  • Cbg-
Description
The loxP-flanked exon 2 of Serpina6tm1Mmp, containing the entire protein coding sequence, has been excised by Cre recombinase. Quantitative real-time PCR analysis of liver mRNA detects no transcripts from the targeted gene in homozygous mutant mice and ~50% of wild-type transcript levels in heterozygous mice. Immunoblot analysis of plasma of homozygous mutant, heterozygous and wild-type mice yields confirmatory results for the for the protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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