Allele/Variant

Clcn5tm6.1Tjj

Species
Mus musculus
Symbol
Clcn5tm6.1Tjj
Category
allele
Allele of gene
Clcn5
Transgenic Constructs
None
Synonyms
  • clcn5lox
Description
A loxP site was inserted downstream of exon 9 and exon 11 was replaced with one containing nucleotide substitutions that result in the amino acid substitution of glutamic acid for tyrosine at position 672 (Y672E). An additional loxP site was inserted downstream of exon 12. An FRT flanked neo cassette inserted downstream of the modified exon 11 was removed by flp mediated recombination leaving exon 10, the modified exon 11, and exon 12 floxed.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations