Version: 8.0.0
Date: Tue Jan 28 2025
Hprt1tm45(Ple67-lacZ)Ems
MGI:4834831
Allele of Hprt1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Hprt1tm45(Ple67-lacZ)Ems

Species
Mus musculus
Symbol
Hprt1tm45(Ple67-lacZ)Ems
Category
allele
Allele of gene
Hprt1
Transgenic Constructs
None
Synonyms
  • FEV-D-lacZ
  • Hprttm45(mEMS3906)Ems
Description
The Ple67-lacZ transgene (pEMS1539) was designed with the 2242 bp Ple67 minipromoter (FEV-D; derived from a portion of the promoter from the FEV (ETS oncogene family) (FEV) gene) upstream of a frt-flanked beta-galactosidase (lacZ) gene, an SV40 early polyA signal, and a human HPRT complementary sequence (containing exon1, intron1, exon2, and part of intron2). This construct was targeted as a single copy knockin to the Hprtb-m3 mutant locus on the X chromosome.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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