Hprt1^{tm39(Ple24-lacZ)Ems}

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Species

Mus musculus

Symbol

Hprt1^{tm39(Ple24-lacZ)Ems}

Category

allele

Allele of gene

Hprt1

Transgenic Constructs

None

Synonyms

• CCKBR-C-lacZ
• Hprt^{tm39(4699)Ems}

Show All 3

Description

The Ple24-lacZ transgene (pEMS1495) was designed with the 3813 bp Ple24 minipromoter (CCKBR-C; derived from a portion of the promoter of the CCKBR gene and two downstream putative regulatory elements from the Gastrin/cholecystokinin type B receptor (CCKBR) gene) upstream of a frt-flanked beta-galactosidase (lacZ) gene, an SV40 early polyA signal, and a human HPRT complementary sequence (containing exon1, intron1, exon2, and part of intron2). This construct was targeted as a single copy knockin to the Hprt^b-m3 mutant locus on the X chromosome.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations