Grhl3^tm2.1Jane

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Species

Mus musculus

Symbol

Grhl3^tm2.1Jane

Category

allele

Allele of gene

Grhl3

Transgenic Constructs

None

Synonyms

• Grhl3^2ki

Description

An 1808 bp cDNA fragment of the mouse Grhl2 gene was inserted such that the codon 12 of exon 2 of Grhl3 was fused to the corresponding codon of Grhl2. This insertion replaced part of exon 2 and all of intron 3 and exon 3. In addition a floxed neo cassette was inserted after the cDNA and then removed by Cre mediated recombination. RT-PCR analysis confirmed the expression of the fusion gene in homozygous and heterozygous mice and absence of expression of the endogenous gene in homozygous mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations