Hprt1^{tm57(Ple26-lacZ)Ems}

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Species

Mus musculus

Symbol

Hprt1^{tm57(Ple26-lacZ)Ems}

Category

allele

Allele of gene

Hprt1

Transgenic Constructs

None

Synonyms

• CCL27-lacZ
• Hprt^{tm57(mEMS4649)Ems}

Show All 3

Description

The Ple26-lacZ transgene (pEMS1497) was designed with the 3252 bp Ple26 minipromoter (CCL27-A; derived from one upstream and two downstream putative regulatory subregions along with a section of the promoter from the human chemokine (C-C motif) ligand 27 [CCL27] gene) upstream of a frt-flanked beta-galactosidase (lacZ) gene, an SV40 early polyA signal, and a human HPRT complementary sequence (containing exon1, intron1, exon2, and part of intron2). This construct was targeted as a single copy knockin to the Hprt^b-m3 mutant locus on the X chromosome.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations