Version: 8.0.0
Date: Tue Jan 28 2025
Fbn1tm1.2Lysa
MGI:4839045
Allele of Fbn1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Fbn1tm1.2Lysa

Species
Mus musculus
Symbol
Fbn1tm1.2Lysa
Category
allele
Allele of gene
Fbn1
Transgenic Constructs
None
Synonyms
  • GT8
Description
A lox66 site was inserted upstream of exon 33. The following vector was inserted into intron 34 (5' through 3'): eGFP, exon 33 splice acceptor site, lox77 site, and FRT flanked neo cassette. Flp mediated recombination removed the neo cassette. Cre mediated recombination inverted the region between lox66 and lox77, bringing eGFP into frame after exon 32. The predicted product is truncated after the 17th calcium-binding epidermal growth factor-like domain (cbEGF17) and called GT8 ("green truncated" from founder mouse 8).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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