Allele/Variant

Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo

Species
Mus musculus
Symbol
Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
The mouse promoter drives neuronal expression of human SOD1 containing the G37R mutation found in patients with familial amyotrophic lateral sclerosis. This transgene was co-injected with Tg(PSEN1)S8-4Dbo. Two lines were generated (39 and 110).
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations