Allele/Variant

Evx2/Hoxd13tm5(Hoxd11/lacZ)Ddu

Species
Mus musculus
Symbol
Evx2/Hoxd13tm5(Hoxd11/lacZ)Ddu
Category
allele
Allele of gene
Evx2
Transgenic Constructs
None
Synonyms
  • TgH[d-11/lac/neo]Ge
Description
The E. coli lacZ gene was inserted, with translational reading frames aligned, into the first exon of the mouse Hoxd11 gene in a construct containing the entire Hoxd11 transcription unit and its known cis-acting 5'and 3' regulatory sequences. This fusion gene, followed by a loxP-flanked PGK-neo selection cassette, was targeted to the intergenic region between the transcription initiation sites of Evx2 and Hoxd13, at the 5' extremity of the Hoxd complex.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
brachydactylyMGI
brachyphalangiaMGI
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Disease Associations

No data available