Allele/Variant

Mesp2tm17.1(VP16/Rbpj)Ysa

Species
Mus musculus
Symbol
Mesp2tm17.1(VP16/Rbpj)Ysa
Category
allele
Allele of gene
Mesp2
Transgenic Constructs
Synonyms
  • deltaneoMesp2-VP16
  • Mesp2VP16
Description
The entire gene was replaced with a fusion of the viral coactivator VP16 activation domain and Rbpj, a floxed neo cassette, and a poly A tail. Cre mediated recombination removed the neo cassette. This allele expresses a constitutively active form of Rbpj. Whole mount in situ hybridization analysis confirmed the absence of Mesp2 expression in E11.5 homozygous embryos.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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