Allele/Variant

Fam3btm1Bkht

Species
Mus musculus
Symbol
Fam3btm1Bkht
Category
allele
Allele of gene
Fam3b
Transgenic Constructs
None
Synonyms
  • PANDER-
Description
Exons 1 and 2 were replaced with a neomycin selection cassette in reverse orientation. This removed the transcriptional and translational start sites and the first 54 amino acids including the secretion signal peptide and helix A. mRNA was not detected in pancreatic islets, small intestine, liver, spleen, kidney, and brain by RT-PCR. Western blot analysis of pancratic islets demonstrated the absence of full length protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations