Ces1c^tm1.1Loc

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Species

Mus musculus

Symbol

Ces1c^tm1.1Loc

Category

allele

Allele of gene

Ces1c

Transgenic Constructs

None

Synonyms

None

Description

A targeting vector was designed to insert a loxP site upstream of exon 5, and a neomycin resistance (neo) cassette followed by a single loxP site downstream of exon 5. Cre-mediated recombination removed exon 5 and the neo cassette. This deletion is predicted to abolish protein function. The absence of carboxylesterase activity in the plasma was confirmed by enzymatic assay.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations