Allele/Variant

Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • Rosa26-Rheb(S16H)
  • Rosa26-Rheb1k
Description
A construct consisting of the CMV beta-actin enhancer/promoter, a floxed PGK-EM7-neo-tPA cassette, a myc tagged Rheb cDNA containing an S16H mutation, and an SV40 poly(A) signal, was inserted via homologous recombination. Expression of the Rheb cDNA is silenced prior to cre mediated recombination.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations