Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw
MGI:4939476
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • Rosa26-Rheb(S16H)
  • Rosa26-Rheb1k
Description
A construct consisting of the CMV beta-actin enhancer/promoter, a floxed PGK-EM7-neo-tPA cassette, a myc tagged Rheb cDNA containing an S16H mutation, and an SV40 poly(A) signal, was inserted via homologous recombination. Expression of the Rheb cDNA is silenced prior to cre mediated recombination.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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