Version: 8.0.0
Date: Tue Jan 28 2025
Trp53tm1.1Awbr
MGI:4941040
Allele of Trp53
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Trp53tm1.1Awbr

Species
Mus musculus
Symbol
Trp53tm1.1Awbr
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53mdetlapro
  • Trp53mdeltapro
Description
A loxP site was inserted upstream of exon 3. Exon 4 was replaced with a modified exon 4 that lacked 93 bps encoding amino acids 58 through 88 of the proline rich domain (mdeltapro). An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the modified exon 4. Flp-mediated recombination removed the neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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