Allele/Variant

Sosttm1Lhe

Species
Mus musculus
Symbol
Sosttm1Lhe
Category
allele
Allele of gene
Sost
Transgenic Constructs
None
Synonyms
None
Description
The genomic region of coding sequence (CDS) extending from exon 1 to exon 2 of the gene was replaced with a LacZ gene and a PGK-Neomycin cassette by targeted homologous recombination. RT-PCR confirmed absence of transcript, and Western blot confirmed absence of protein product in femur. This is a null allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations