Version: 8.0.0
Date: Tue Jan 28 2025
Tg(LRRK2*G2019S)1Cjli
MGI:4942189Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(LRRK2*G2019S)1Cjli

Species
Mus musculus
Symbol
Tg(LRRK2*G2019S)1Cjli
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • G/S LRRK2
Description
A 188 Kb bacterial artificial chromosome (BAC) containing the entire human LRRK2 (leucine-rich repeat kinase 2) gene was modified by targeted mutation of the LRRK2 locus to harbor the LRRK2 G2019S mutation associated with autosomal dominant, late-onset Parkinson's disease.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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