Allele/Variant

Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

PPFP
Tg(CAG-EGFP,-PAX8/PPARG)1Rjk

Description

The CAG promoter drives expression of a floxed EGFP followed by the fusion of human PAX8 and PPARG. Cre-mediated recombination is required to remove the floxed EGFP cassette and allow for expression of the fusion protein. This fusion protein is expressed in 35% of human follicular thyroid carcinomas.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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