Nrxn3^tm4.1Sud

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Species

Mus musculus

Symbol

Nrxn3^tm4.1Sud

Category

allele

Allele of gene

Nrxn3

Transgenic Constructs

None

Synonyms

• Nrx3^ss4+
• NS4

Description

A targeting vector was designed to insert a loxP site upstream of exon 20 (alternative splice site 4) followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 20. The less common splice acceptor sequence of exon 20 (TGTTTTTTAAACTTTAAAG) was substituted with a much more common one (TGTTTTTTCGTCTTCCTAG) to make the exon always incorporated in the transcript.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations