Allele/Variant

Juptm1.2Glr

Species
Mus musculus
Symbol
Juptm1.2Glr
Category
allele
Allele of gene
Jup
Transgenic Constructs
None
Synonyms
None
Description
A loxP site was inserted upstream of exon 1, and a loxP site and an FRT-flanked neo cassette were introduced into intron 1 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. Cre mediated recombination removed exon 1. Western blot analysis of E12.5 homozygous embryos confirmed the absence of protein expression.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations