Allele/Variant

Col1a1tm1(tetO-Tcfap2c)Hsc

Species
Mus musculus
Symbol
Col1a1tm1(tetO-Tcfap2c)Hsc
Category
allele
Allele of gene
Col1a1
Transgenic Constructs
Synonyms
None
Description
RMCE on KH2 cells inserted a cassette that contains a tetracycline responsive element (TRE or tetO) and mouse AP-2gamma (Tcfap2c) cDNA sequence into the 3'UTR. With doxycycline treatment, Tcfap2c expression from the Col1a1 locus is widespread with high levels in skin, intestine and stomach, while lower levels are seen in the heart, spleen, thymus and several other organs. No expression is seen in the brain or testes.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations