Allele/Variant

Cryabtm1.1Ady

Species
Mus musculus
Symbol
Cryabtm1.1Ady
Category
allele
Allele of gene
Cryab
Transgenic Constructs
None
Synonyms
  • alphaB-R120G
Description
Exon 3 was replaced with one in which an A to G transition results in the amino acid transition of arginine to glycine at position 120 (R120G), mimicking a mutation associated with cataracts and desmin-related myopathy (DRM) in humans. Cre-mediated recombination removed the floxed neo cassette inserted downstream of the modified exon 3.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations