Version: 8.0.0
Date: Tue Jan 28 2025
Nek7tm1Mot
MGI:4999797
Allele of Nek7
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Nek7tm1Mot

Species
Mus musculus
Symbol
Nek7tm1Mot
Category
allele
Allele of gene
Nek7
Transgenic Constructs
None
Synonyms
None
Description
Most of exons 3 and 4 of the gene is replaced with b-galactosidase (b-gal)-Neo resistance cassette, which deletes 1630 bp and insert premature termination of Nek7 coding at amino-acid 75 but leaving intact the splice acceptor site of exon 3 and the splice donor site of exon 4. Western blot confirmed absence of protein product in cultured MEF. This is a null allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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