Allele/Variant

Gbp2b^tm1Tigm

Species: Mus musculus
Symbol: Gbp2b^tm1Tigm
Category: allele
Allele of gene: Gbp2b
Transgenic Constructs: None
Synonyms: None
Description: Exons 2 through 4 were replaced with a neo/lacZ cassette. Reduced protein expression in IFN-gamma-activated bone marrow macrophages was confirmed by western blot analysis.
Additional Information: Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype

Annotation details

Source

References

abnormal macrophage physiology

MGI

PMID:21551061

diarrhea

MGI

PMID:21551061

increased susceptibility to bacterial infection

MGI

PMID:21551061

increased susceptibility to bacterial infection induced morbidity/mortality

MGI

PMID:21551061

weight loss

MGI

PMID:21551061

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Disease Associations

Association	Disease Qualifier	Disease	Annotation details	Evidence	Source	References
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