Version: 8.0.0
Date: Tue Jan 28 2025
Hprt1tm75(Ple143-lacZ)Ems
MGI:5050094
Allele of Hprt1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Hprt1tm75(Ple143-lacZ)Ems

Species
Mus musculus
Symbol
Hprt1tm75(Ple143-lacZ)Ems
Category
allele
Allele of gene
Hprt1
Transgenic Constructs
None
Synonyms
  • Hprttm75(mEMS4990)Ems
  • NR2F2-lacZ
Description
The Ple143-lacZ transgene (bEMS85) was designed with the Ple143 MaxiPromoter (derived from the BAC RP11-134D15 that contains the whole NR2F2 gene plus 117kb upstream and 80kb downstream sequences) upstream of a frt-flanked beta-galactosidase (lacZ) gene, an SV40 early polyA signal, and a human HPRT complementary sequence (containing exon1, intron1, exon2, and part of intron2). This construct was targeted as a single copy knockin to the Hprtb-m3 mutant locus on the X chromosome.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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