Allele/Variant

Aurkbtm2.2Mama

Species
Mus musculus
Symbol
Aurkbtm2.2Mama
Category
allele
Allele of gene
Aurkb
Transgenic Constructs
None
Synonyms
  • Aurkb(Z)
Description
Exons 2 - 4 were flanked with wild-type and mutant loxP sites, an inverted IRES-lacZ cassette was inserted between exons 4 and 5 inside the loxP sites, and an FRT flanked neo cassette was inserted between exons 4 and 5 outside the loxP sites via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination inverted the IRES-lacZ cassette and removed exons 2 -4.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
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