Allele/Variant

Trp53tm3Att

Species
Mus musculus
Symbol
Trp53tm3Att
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53LSL-53,54
Description
A loxP site flanked puromycin resistance gene/transcription stop cassette was inserted into intron 1 and mutations were created in exon 4 altering codon 53 from phenylalanine to glutamine (p.F53Q) and codon 54 from phenylalanine to serine (p.F54S). The second transactivation domain is incapacitated once the stop sequences are removed by cre expression.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

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    Disease Associations

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