Allele/Variant

Klf5tm1.1Jwel

Species
Mus musculus
Symbol
Klf5tm1.1Jwel
Category
allele
Allele of gene
Klf5
Transgenic Constructs
None
Synonyms
  • KD
  • Klf5del
Description
A loxP flanked Hprt selection cassette upstream of exon1 and an additional loxP site downstream of exon 2 are inserted by homologous recombination. Transient Cre expression deleted exons 1 and 2. Although the cre-mediated deletion is predicted to result in the production of an in-frame transcript, the gene product from this allele is predicted to be non functional. Loss of protein was confirmed by immunostaining in early embryos.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations