Allele/Variant

Gt(ROSA)26Sortm2(H1/tetO-RNAi:lacZ)Jcbr

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm2(H1/tetO-RNAi:lacZ)Jcbr
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
None
Synonyms
  • LacZshRNADOX
Description
A construct containing a short hairpin RNA targeting lacZ driven by the H1/tetO operator fusion promoter followed by a CAG promoter driving expression of the tetR regulatory cassette was inserted into the locus by flp-mediated recombination via RMCE with Gt(ROSA)26Sortm1(CAG-flpe)Arte. Doxycycline-treatment is required to activate expression of the shRNA.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations