Version: 8.0.0
Date: Tue Jan 28 2025
Glra1tm1.1Geh
MGI:5293666
Allele of Glra1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Glra1tm1.1Geh

Species
Mus musculus
Symbol
Glra1tm1.1Geh
Category
allele
Allele of gene
Glra1
Transgenic Constructs
None
Synonyms
  • alpha1(Q266I)
Description
A targeting construct was designed to insert a frt-flanked neomycin (neo) resistance cassette in opposite orientation to the gene, downstream of exon 7 of the glycine receptor, alpha 1 subunit (Glra1) gene. Nucleotide substitutions (CAG to ATC) introduced in exon 7 resulted in the amino acid mutation Q266I. Flp-mediated recombination removed the neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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