Allele/Variant

Usp2tm1.1Ssw

Species
Mus musculus
Symbol
Usp2tm1.1Ssw
Category
allele
Allele of gene
Usp2
Transgenic Constructs
None
Synonyms
None
Description
An FRT flanked neomycin/kanamycin selection cassette and loxP site were inserted upstream of exon 4 and a loxP site was inserted downstream of exon 6 via homologous recombination. Cre mediated recombination deleted exons 4 - 6. RT-PCR and western blot analysis confirmed the absence of wild-type RNA and protein expression in testes and MEFs, respectively, from homozygous mice. RT-PCR analysis did detect expression of a small transcript containing exons 7 and 9 in testes from homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations