Allele/Variant

Gt(ROSA)26Sortm3(tetO-EGFP,-RNAi:T)Bgh

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm3(tetO-EGFP,-RNAi:T)Bgh
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
None
Synonyms
  • KD3-T
Description
Recombinase mediated cassette exchange was used to insert a tetO, CAG regulated EGFP followed by a short hairpin RNAi specific for the Brachyury (T) gene followed by a PGK promoter into the Gt(ROSA)26Sortm1Bgh allele. The tetracycline silencer prevents expression of both the reporter and the shRNAi until mice are treated with doxycycline.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations