Allele/Variant

Cd68tm1Xfen

Species
Mus musculus
Symbol
Cd68tm1Xfen
Category
allele
Allele of gene
Cd68
Transgenic Constructs
None
Synonyms
None
Description
Exons 1 and 2 were replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on bone marrow-derived macrophage.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal osteoclast morphology
MGI
abnormal osteoclast physiology
MGI
abnormal trabecular bone morphology
MGI
decreased bone mineral density
MGI
decreased bone resorption
MGI
increased bone mineralizationMGI
increased bone trabecula number
MGI
increased bone volume
MGI
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Disease Associations

No data available