Version: 8.0.0
Date: Tue Jan 28 2025
Leprtm5Mgmj
MGI:5301119
Allele of Lepr
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Leprtm5Mgmj

Species
Mus musculus
Symbol
Leprtm5Mgmj
Category
allele
Allele of gene
Lepr
Transgenic Constructs
None
Synonyms
  • leprF1077
Description
The targeting vector contained a nucleotide substitution that results in the amino acid substitution of phenyalanine for tyrosine at position 1077 (Y1077F) and a floxed NEO cassette. This mutation is predicted to abolish STAT5 activation by the mutated protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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