Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Mt1-IL6)28Gci
MGI:5302421Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Mt1-IL6)28Gci

Species
Mus musculus
Symbol
Tg(Mt1-IL6)28Gci
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • MT-1/hIL-6
Description
This transgene consists of the human IL6 cDNA under the control of the mouse metallothionein-1 promoter. A 1.7-kb DNA fragment corresponding to the 3' portion of human beta-globin gene is also inserted downstream of the IL6 cDNA to stabilize the IL6 mRNA. Human IL6 mRNA is only detected in the liver.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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