Allele/Variant

Tg(RP11-209M4)AGglo

Species
Mus musculus
Symbol
Tg(RP11-209M4)AGglo
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • SOST TG
  • SOSTwt
Description
The transgene contains the wild-type human BAC RP11-209M4, which contains SOST and the 3' end of MEOX. RT-PCR and quantitative PCR confirmed that all lines express human SOST in the mineralized bone of neonatal and adult mice (skull, rib, and femur) and in the adult kidney. No expression of human MEOX was detected. Three lines were generated (A, B, and an unnamed line). Founder line A was analyzed for expression.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations