Allele/Variant

Pax7tm1.1(HBEGF,-EYFP)Mal

Species
Mus musculus
Symbol
Pax7tm1.1(HBEGF,-EYFP)Mal
Category
allele
Allele of gene
Pax7
Transgenic Constructs
Synonyms
  • Pax7DTR
  • Pax7tm1.1(HBEGF)Mal
Description
Sequence for the human diphtheria toxin receptor (HBEGF) cDNA, an IRES, the EYFP fluorescent reporter gene, a loxP site, the mouse Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1) promoter, the cre recombinase gene, a neomycin resistance gene cassette, and a second loxP site, was inserted after the ATG translation start site, abolishing endogenous translation of the host gene in the allele. Cre-mediated recombination in the male germline removed the cre+neo cassette. No YFP expression was detected.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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