Allele/Variant

Igf2tm4Wrk

Species
Mus musculus
Symbol
Igf2tm4Wrk
Category
allele
Allele of gene
Igf2
Transgenic Constructs
None
Synonyms
  • Rr15tm4Wrk
  • S1.2Neo
Description
A loxP-flanked neomycin resistance cassette has been inserted into the fourth of five HpaII sites within the LRRFIP1/GCF2 (leucine-rich repeat in FLII-interacting protein 1/GC-binding factor 2) repressor protein consensus binding sequence in the first differentially methylated region (DMR1) upstream of the imprinted insulin-like growth factor 2 (Igf2) gene.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal imprinting
MGI
decreased birth weight
MGI
prenatal growth retardation
MGI
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Disease Associations

No data available