Lox^b2b370.2Clo

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Species

Mus musculus

Symbol

Lox^b2b370.2Clo

Category

allele

Allele of gene

Lox

Transgenic Constructs

None

Synonyms

• Lox^{c.G854T/p.C285F}

Description

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b370Clo. The molecular lesion for this subline is a G to T substitution at coding nucleotide 854 in exon 3 of the cDNA (c.854G>T, NM_010728). This changes the cysteine residue to phenylalanine at position 285 of the encoded protein (p.C285F).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations