Version: 8.0.0
Date: Tue Jan 28 2025
Col1a1tm1(tetO-YAP1*)Fcam
MGI:5316453
Allele of Col1a1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Col1a1tm1(tetO-YAP1*)Fcam

Species
Mus musculus
Symbol
Col1a1tm1(tetO-YAP1*)Fcam
Category
allele
Allele of gene
Col1a1
Transgenic Constructs
Synonyms
  • TetO-YAP1
  • Yap1-S127A
Description
RMCE on KH2 cells inserted a cassette, which contained a tetracycline response element driving doxycycline-inducible expression of the human cDNA with nucleotide substitutions that result in the amino acid substitution of alanine for serine at position 127 (S127A), into the 3'UTR. This mutation produces a protein with increased nuclear localization and transcriptional activity compared with the wild-type protein.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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