Allele/Variant

Nototm2.1(Foxj1)Gos

Species
Mus musculus
Symbol
Nototm2.1(Foxj1)Gos
Category
allele
Allele of gene
Noto
Transgenic Constructs
None
Synonyms
  • NotoFoxj1
Description
Most of exon 1 and all of exon 2 were replaced with the coding sequence for Foxj1, an IRES2-tdtomato, and an FRT flanked neo cassette. Flp mediated recombination removed the neo cassette. Expression of tdtomato is detected in the node in heterozygous embryos. Expression of Foxj1 mRNA is detected in homozygous embryos at E7.5-8.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal embryonic cilium location or orientationMGI
abnormal left-right axis patterningMGI
abnormal motile primary cilium morphologyMGI
abnormal motile primary cilium physiologyMGI
abnormal primitive node morphologyMGI
kinked tailMGI
short tailMGI
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Disease Associations

No data available