Allele/Variant

Tg(Kap-Ppara/AGT)562Dpo

Species
Mus musculus
Symbol
Tg(Kap-Ppara/AGT)562Dpo
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • Kap2-Ppara
Description
A 1542 bp fragment of the Kap promoter drives expression of a FLAG-tagged Ppara gene and exons 3-5 and 3' untranslated region of the human angiotensin gene. Three lines were generated (560, 561, 562). This line had the highest level of transgene expression in the kidney. Testosterone treatment induces higher levels of transgene expression in the kidneys of female mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations