Allele/Variant

Hk2tm1.1Uku

Species
Mus musculus
Symbol
Hk2tm1.1Uku
Category
allele
Allele of gene
Hk2
Transgenic Constructs
None
Synonyms
  • Hk2lox
  • neoless Hk2lox
Description
A loxP-flanked neomycin resistance (neo) cassette was inserted into intron 3 and a third loxP site into intron 10. The neo cassette was deleted by Cre recombinase in vivo, leaving a single loxP site in intron 3. Crossing mice with this allele to animals expressing Cre recombinase will result in deletion of exons 4-10, inactivating the gene, in the offpring in the tissues or cell types where Cre is expressed.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations