Allele/Variant

Gnastm1.1Plag

Species
Mus musculus
Symbol
Gnastm1.1Plag
Category
allele
Allele of gene
Gnas
Transgenic Constructs
None
Synonyms
  • Gnasxltm2Pla
  • XLlacZGT
Description
Exon A20 was replaced with a gene trap vector containing (5' to 3'): lox2272 site, loxP site, FRT site, lacZ gene, and cDNA encoding exon 2SA. Flp-mediated recombination removed the neo cassette. qRT-PCR confirmed a 90% downregulation of transcript expression.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations