Allele/Variant

Drd1tm1.1(IL2RA/Venus)Koba

Species
Mus musculus
Symbol
Drd1tm1.1(IL2RA/Venus)Koba
Category
allele
Allele of gene
Drd1
Transgenic Constructs
None
Synonyms
  • Drd1KI
Description
A Venus reporter fused to human IL2RA with a polydaenylation sequence and a floxed neo cassette was inserted upstream of exon 2. Cre-mediated recombination removed the neo cassette. Treatment with a recombinant immunotoxin (variable anti-IL2RA regions fused to a bacterial exotoxin fragment) results in ablation of cells expressing this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations