Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm2(Notch2)Ryn
MGI:5430391
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm2(Notch2)Ryn

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm2(Notch2)Ryn
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • Gt(ROSA)26Sortm2(Notch2)Ryni
  • Gt(Rosa)26Sortm1(Notch2)Nis
Description
The floxed neo/STOP cassette and a flag-tagged Notch2 fragment, which encompassed amino acids 1701 to 2470 and lacked the transmembrane domain or S3 cleavage site but contained the intact transactivation domain and C-terminal PEST sequences, were knocked into the locus.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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