Version: 8.0.0
Date: Tue Jan 28 2025
Opn1swtm1.1Pugh
MGI:5431113
Allele of Opn1sw
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Opn1swtm1.1Pugh

Species
Mus musculus
Symbol
Opn1swtm1.1Pugh
Category
allele
Allele of gene
Opn1sw
Transgenic Constructs
None
Synonyms
  • Opn1swF81Y
Description
Exon 1 was replaced with one in which an A to T transition results in the amino acid substitution of tyrosine for phenylalanine at position 81 (F81Y). An FRT-flanked neo cassette was inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette. Western blot analysis confirmed a 2-fold reduction in protein expression.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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