Allele/Variant

Tg(Erv4-cre/ERT2*)657Slp

Species
Mus musculus
Symbol
Tg(Erv4-cre/ERT2*)657Slp
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • 2C::ERT2-Cre-ERT2
  • Tg(MuERV-L-ERT2-Cre-ERT2)657Slp
Description
The 5' LTR of murine endogenous retrovirus with leucine tRNA primer (MuERV-L; MERVL; Erv4) and the primer binding site drive expression of tamoxifen-inducible Cre recombinase (2C::ERT2-Cre-ERT2). Two flanking ERT2 segments were inserted to make Cre activation less leaky. The transgenic vector was injected into CB6 (BALB/c and C57BL/6) embryos and the resultant strain was subsequently maintained on the same mixed genetic background by the donating laboratory. This is founder line 657.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
  • Erv4
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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